SNTA1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SCN5A
Gene Ontology Biological Process
- AV node cell to bundle of His cell communication [IMP]
- SA node cell to atrial cardiac muscle cell communication [IMP]
- brainstem development [ISS]
- bundle of His cell to Purkinje myocyte communication [IMP]
- cardiac muscle cell action potential involved in contraction [IMP]
- cardiac muscle contraction [IMP]
- cardiac ventricle development [ISS]
- cellular response to calcium ion [IDA]
- cerebellum development [ISS]
- membrane depolarization [IDA]
- membrane depolarization during SA node cell action potential [ISS]
- membrane depolarization during action potential [IDA]
- membrane depolarization during cardiac muscle cell action potential [IMP]
- neuronal action potential [IBA]
- odontogenesis of dentin-containing tooth [ISS]
- positive regulation of action potential [ISS]
- positive regulation of epithelial cell proliferation [ISS]
- positive regulation of sodium ion transport [IDA]
- regulation of atrial cardiac muscle cell membrane depolarization [IMP]
- regulation of atrial cardiac muscle cell membrane repolarization [IMP]
- regulation of cardiac muscle cell contraction [IMP]
- regulation of heart rate [IMP]
- regulation of heart rate by cardiac conduction [IMP]
- regulation of sodium ion transmembrane transport [IDA]
- regulation of ventricular cardiac muscle cell membrane depolarization [IMP]
- regulation of ventricular cardiac muscle cell membrane repolarization [IMP]
- response to denervation involved in regulation of muscle adaptation [ISS]
- sodium ion transmembrane transport [IDA, IMP]
- sodium ion transport [IDA]
- telencephalon development [ISS]
- ventricular cardiac muscle cell action potential [IMP]
Gene Ontology Molecular Function- ankyrin binding [IDA]
- calmodulin binding [IPI]
- enzyme binding [IPI]
- fibroblast growth factor binding [IPI]
- ion channel binding [IPI]
- nitric-oxide synthase binding [IPI]
- protein binding [IPI]
- protein kinase binding [IPI]
- scaffold protein binding [IPI]
- ubiquitin protein ligase binding [IPI]
- voltage-gated sodium channel activity [IDA]
- voltage-gated sodium channel activity involved in cardiac muscle cell action potential [IDA, IMP]
- ankyrin binding [IDA]
- calmodulin binding [IPI]
- enzyme binding [IPI]
- fibroblast growth factor binding [IPI]
- ion channel binding [IPI]
- nitric-oxide synthase binding [IPI]
- protein binding [IPI]
- protein kinase binding [IPI]
- scaffold protein binding [IPI]
- ubiquitin protein ligase binding [IPI]
- voltage-gated sodium channel activity [IDA]
- voltage-gated sodium channel activity involved in cardiac muscle cell action potential [IDA, IMP]
Gene Ontology Cellular Component
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.
Syntrophins are cytoplasmic peripheral membrane proteins of the dystrophin-associated protein complex (DAPC). Three syntrophin isoforms, alpha1, beta1, and beta2, are encoded by distinct genes. Each contains two pleckstrin homology (PH) domains, a syntrophin-unique (SU) domain, and a PDZ domain. The name PDZ comes from the first three proteins found to contain repeats of this domain (PSD-95, Drosophila discs large protein, ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SCN5A SNTA1 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID