CDC24
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
BUD6
Gene Ontology Biological Process
- actin filament bundle assembly [IGI, IMP]
- astral microtubule organization [IMP]
- bipolar cellular bud site selection [IMP]
- budding cell apical bud growth [IGI, IMP]
- establishment of cell polarity [IMP]
- extrachromosomal circular DNA localization involved in cell aging [IMP]
- positive regulation of actin cytoskeleton reorganization [IGI, IMP]
- positive regulation of formin-nucleated actin cable assembly [IDA, IGI]
- pseudohyphal growth [IMP]
- regulation of protein localization [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Cdc24 interacts with septins to create a positive feedback loop during bud site assembly in yeast.
Yeast cells select the position of their new bud at the beginning of each cell cycle. The recruitment of septins to this prospective bud site is one of the critical events in a complex assembly pathway that culminates in the outgrowth of a new daughter cell. During recruitment, septin rods follow the high concentration of Cdc42GTP that is generated by ... [more]
Throughput
- Low Throughput
Additional Notes
- split-ubiquitin
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CDC24 BUD6 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1809 | BioGRID | 354594 | |
| BUD6 CDC24 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.3405 | BioGRID | 2058406 | |
| CDC24 BUD6 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1551 | BioGRID | 1958072 |
Curated By
- BioGRID