BAIT
STON2
STN2, STNB, STNB2
stonin 2
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
SYT1
P65, SVP65, SYT
synaptotagmin I
GO Process (10)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- detection of calcium ion [TAS]
- fast, calcium ion-dependent exocytosis of neurotransmitter [ISS]
- glutamate secretion [TAS]
- neurotransmitter secretion [TAS]
- positive regulation of synaptic transmission [ISS]
- protein homooligomerization [TAS]
- regulation of exocytosis [TAS]
- regulation of regulated secretory pathway [ISS]
- regulation of synaptic transmission, glutamatergic [ISS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- clathrin-sculpted acetylcholine transport vesicle membrane [TAS]
- clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [TAS]
- clathrin-sculpted glutamate transport vesicle membrane [TAS]
- clathrin-sculpted monoamine transport vesicle membrane [TAS]
- endocytic vesicle membrane [TAS]
- neuron projection [ISS]
- plasma membrane [TAS]
- synaptic vesicle [TAS]
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Human stoned B interacts with AP-2 and synaptotagmin and facilitates clathrin-coated vesicle uncoating.
Synaptic vesicle biogenesis involves the recycling of synaptic vesicle components by clathrin-mediated endocytosis from the presynaptic membrane. stoned B, a protein encoded by the stoned locus in Drosophila melanogaster has been shown to regulate vesicle recycling by interacting with synaptotagmin. We report here the identification and characterization of a human homolog of stoned B (hStnB). Human stoned B is a ... [more]
EMBO Rep. Jul. 01, 2001; 2(7);634-40 [Pubmed: 11454741]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| STON2 SYT1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID