BAIT
S100A13
S100 calcium binding protein A13
GO Process (4)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SYT1
P65, SVP65, SYT
synaptotagmin I
GO Process (10)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- detection of calcium ion [TAS]
- fast, calcium ion-dependent exocytosis of neurotransmitter [ISS]
- glutamate secretion [TAS]
- neurotransmitter secretion [TAS]
- positive regulation of synaptic transmission [ISS]
- protein homooligomerization [TAS]
- regulation of exocytosis [TAS]
- regulation of regulated secretory pathway [ISS]
- regulation of synaptic transmission, glutamatergic [ISS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- clathrin-sculpted acetylcholine transport vesicle membrane [TAS]
- clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [TAS]
- clathrin-sculpted glutamate transport vesicle membrane [TAS]
- clathrin-sculpted monoamine transport vesicle membrane [TAS]
- endocytic vesicle membrane [TAS]
- neuron projection [ISS]
- plasma membrane [TAS]
- synaptic vesicle [TAS]
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress.
Fibroblast growth factor (FGF) 1 is known to be released in response to stress conditions as a component of a multiprotein aggregate containing the p40 extravescicular domain of p65 synaptotagmin (Syt) 1 and S100A13. Since FGF1 is a Cu2+-binding protein and Cu2+ is known to induce its dimerization, we evaluated the capacity of recombinant FGF1, p40 Syt1, and S100A13 to ... [more]
J. Biol. Chem. Jul. 06, 2001; 276(27);25549-57 [Pubmed: 11432880]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| S100A13 SYT1 | Co-purification Co-purification An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps. | Low | - | BioGRID | 275971 |
Curated By
- BioGRID