BAIT
CSNK2B
CK2B, CK2N, CSK2B, G5A, DADB-127H9.2
casein kinase 2, beta polypeptide
GO Process (13)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
- adiponectin-activated signaling pathway [IDA]
- axon guidance [TAS]
- cellular protein complex assembly [NAS]
- endothelial tube morphogenesis [IMP]
- mitotic cell cycle [TAS]
- negative regulation of blood vessel endothelial cell migration [IDA]
- negative regulation of cell proliferation [TAS]
- positive regulation of activin receptor signaling pathway [IMP]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IDA]
- protein phosphorylation [TAS]
- regulation of DNA binding [NAS]
- regulation of protein kinase activity [NAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FAF1
HFAF1s, UBXD12, UBXN3A, hFAF1, CGI-03
Fas (TNFRSF6) associated factor 1
GO Process (7)
GO Function (7)
GO Component (5)
Gene Ontology Biological Process
- cell death [IMP]
- cytoplasmic sequestering of NF-kappaB [IMP]
- positive regulation of apoptotic process [NAS]
- positive regulation of protein complex assembly [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [NAS]
- regulation of protein catabolic process [IMP]
- regulation of protein kinase activity [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Interactions of protein kinase CK2beta subunit within the holoenzyme and with other proteins.
Protein kinase CK2 is a ubiquitous, highly conserved protein kinase with a tetrameric alpha2beta2 structure. For the formation of this tetrameric complex a beta-alpha dimer seems to be a prerequisite. Using the two-hybrid system and a series of CK2beta deletion mutants, we mapped domains involved in alpha-beta and beta-beta interactions. We also detected an intramolecular beta interaction within the amino ... [more]
Mol. Cell. Biochem. Jan. 01, 1999; 191(1);51-8 [Pubmed: 10094392]
Throughput
- Low Throughput
Curated By
- BioGRID