Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.

Xie C, Zhou M, Lin J, Wu Z, Ding S, Luo J, Zhan Z, Cai Y, Xue S, Song Y

Eukaryotic translation elongation factor 1? (EEF1D), a subunit of the elongation factor 1 complex of proteins, mediates the elongation process of protein synthesis. Besides this canonical role, EEF1D was found overexpressed in many tumors, like hepatocarcinomas and medulloblastomas. In the present study, we demonstrated for the first time that EEF1D may interact with other putative proteins to regulate cell proliferation, ... [more]

Biomed Res Int Oct. 09, 2020; 2020();7804706 [Pubmed: 33029523]

Throughput

  • Low Throughput

Curated By

  • BioGRID