BAIT

HIP1R

huntingtin interacting protein 1 related
GO Process (1)
GO Function (2)
GO Component (6)
Rattus norvegicus

Reconstituted Complex

An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.

Publication

Huntingtin-interacting protein-1-related protein of rat (rHIP1R) is localized in the postsynaptic regions.

Okano A, Usuda N, Furihata K, Nakayama K, Bao Tian Q, Okamoto T, Suzuki T

We cloned a rHIP1R (GenBank Accession No., AB005052) encoding a Sla2/huntingtin-interacting protein (HIP1) family protein from a rat brain cDNA library. Localization of rHIP1R was investigated in the rat brain using an antibody specific to the HIP1R antibody. The rHIP1R protein was enriched in the synaptic plasma membrane fraction along with huntingtin, a synaptic protein and a causal protein for ... [more]

Brain Res Mar. 28, 2003; 967(1-2);210-25 [Pubmed: 12650982]

Throughput

  • Low Throughput

Curated By

  • BioGRID