BAIT
PRPF6
ANT-1, ANT1, C20orf14, Prp6, RP60, SNRNP102, TOM, U5-102K, hPrp6
pre-mRNA processing factor 6
GO Process (8)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- RNA localization [IMP]
- RNA splicing [NAS, TAS]
- RNA splicing, via transesterification reactions [NAS]
- gene expression [TAS]
- mRNA splicing, via spliceosome [IC, TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- spliceosomal complex assembly [NAS]
- spliceosomal tri-snRNP complex assembly [IC, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FXR2
FMR1L2, FXR2P
fragile X mental retardation, autosomal homolog 2
GO Process (1)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.
RNA-binding proteins (RBPs) are crucial factors of post-transcriptional gene regulation and their modes of action are intensely investigated. At the center of attention are RNA motifs that guide where RBPs bind. However, sequence motifs are often poor predictors of RBP-RNA interactions in vivo. It is hence believed that many RBPs recognize RNAs as complexes, to increase specificity and regulatory possibilities. ... [more]
Nucleic Acids Res Dec. 09, 2020; 49(12);6702-6721 [Pubmed: 34133714]
Throughput
- High Throughput
Additional Notes
- Included protein pairs with sumIS score >= 7.1
Curated By
- BioGRID