PREY

CELSR3

CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1
cadherin, EGF LAG seven-pass G-type receptor 3
GO Process (1)
GO Function (1)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens

Co-localization

Interaction inferred from two proteins that co-localize in the cell by indirect immunofluorescence only when in addition, if one gene is deleted, the other protein becomes mis-localized. Also includes co-dependent association of proteins with promoter DNA in chromatin immunoprecipitation experiments.

Publication

Regulation of the protocadherin Celsr3 gene and its role in globus pallidus development and connectivity.

Jia Z, Guo Y, Tang Y, Xu Q, Li B, Wu Q

The globus pallidus (GP) is a central component of basal ganglia whose malfunctions cause a variety of neuropsychiatric disorders as well as cognitive impairments in neurodegenerative diseases such as Parkinson's disease. Here we report that the protocadherin gene Celsr3 is regulated by the insulator CCCTC-binding factor (CTCF) and the repressor neuron-restrictive silencer factor (NRSF, also known as REST) and is ... [more]

Mol Cell Biol Oct. 01, 2014; 34(20);3895-910 [Pubmed: 25113559]

Throughput

  • Low Throughput

Additional Notes

  • ChIP

Curated By

  • BioGRID