BAIT
CALCA
CALC1, CGRP, CGRP-I, CGRP1, CT, KC
calcitonin-related polypeptide alpha
GO Process (28)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- G-protein coupled receptor internalization [IDA]
- activation of adenylate cyclase activity [IDA]
- activation of protein kinase activity [IDA]
- cell-cell signaling [TAS]
- cytosolic calcium ion homeostasis [IDA]
- embryo implantation [IDA]
- endothelial cell migration [IDA]
- endothelial cell proliferation [IDA]
- leukocyte cell-cell adhesion [IDA]
- monocyte chemotaxis [IDA]
- negative regulation of blood pressure [IDA]
- negative regulation of bone resorption [IDA]
- negative regulation of calcium ion transport into cytosol [IDA]
- negative regulation of osteoclast differentiation [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- neurological system process involved in regulation of systemic arterial blood pressure [IDA]
- positive regulation of adenylate cyclase activity [IDA]
- positive regulation of cAMP biosynthetic process [IDA]
- positive regulation of cytosolic calcium ion concentration [IDA]
- positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [IDA]
- positive regulation of interleukin-1 alpha production [IDA]
- positive regulation of interleukin-8 production [IDA]
- positive regulation of macrophage differentiation [IDA]
- positive regulation of vasodilation [IDA]
- protein phosphorylation [IDA]
- receptor internalization [IDA]
- regulation of blood pressure [NAS]
- vasculature development [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
B3GNT3
B3GAL-T8, B3GN-T3, B3GNT-3, HP10328, TMEM3, beta3Gn-T3, UNQ637/PRO1266
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
GO Process (9)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- O-glycan processing [TAS]
- carbohydrate metabolic process [TAS]
- cellular protein metabolic process [TAS]
- glycosaminoglycan metabolic process [TAS]
- keratan sulfate biosynthetic process [TAS]
- keratan sulfate metabolic process [TAS]
- poly-N-acetyllactosamine biosynthetic process [IDA]
- post-translational protein modification [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Status: Pre-Publication Dataset
Quantitative Score
- 0.523554766 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.523554766146238, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Curated By
- BioGRID