CAMKV
TGFBR3
Gene Ontology Biological Process
- BMP signaling pathway [IDA]
- cardiac epithelial to mesenchymal transition [IDA]
- cardiac muscle cell proliferation [ISS]
- cell growth [ISS]
- cell migration [ISS]
- definitive erythrocyte differentiation [ISS]
- definitive hemopoiesis [ISS]
- epithelial to mesenchymal transition [IDA]
- heart morphogenesis [ISS]
- heart trabecula formation [ISS]
- immune response [IMP]
- intracellular signal transduction [IMP]
- liver development [ISS]
- negative regulation of cellular component movement [IDA]
- negative regulation of epithelial cell proliferation [ISS]
- palate development [ISS]
- pathway-restricted SMAD protein phosphorylation [IMP]
- response to follicle-stimulating hormone [IDA]
- response to luteinizing hormone [IDA]
- response to prostaglandin E [IDA]
- transforming growth factor beta receptor signaling pathway [IDA, IMP]
- ventricular cardiac muscle tissue morphogenesis [ISS]
Gene Ontology Molecular Function- PDZ domain binding [ISS]
- SMAD binding [IMP]
- coreceptor activity [IDA]
- glycosaminoglycan binding [ISS, TAS]
- heparin binding [ISS]
- protein binding [IPI]
- transforming growth factor beta binding [IDA]
- transforming growth factor beta receptor activity, type III [IDA]
- transforming growth factor beta receptor binding [ISS]
- transforming growth factor beta-activated receptor activity [IDA]
- type II transforming growth factor beta receptor binding [IDA]
- PDZ domain binding [ISS]
- SMAD binding [IMP]
- coreceptor activity [IDA]
- glycosaminoglycan binding [ISS, TAS]
- heparin binding [ISS]
- protein binding [IPI]
- transforming growth factor beta binding [IDA]
- transforming growth factor beta receptor activity, type III [IDA]
- transforming growth factor beta receptor binding [ISS]
- transforming growth factor beta-activated receptor activity [IDA]
- type II transforming growth factor beta receptor binding [IDA]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.453226845 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.453226845106076, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CAMKV TGFBR3 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9996 | BioGRID | 2230051 | |
| CAMKV TGFBR3 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9997 | BioGRID | 3036758 |
Curated By
- BioGRID