ANLN
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MYH9
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- actin cytoskeleton reorganization [IMP]
- actin filament-based movement [IDA]
- actomyosin structure organization [IDA]
- angiogenesis [IDA]
- axon guidance [TAS]
- blood vessel endothelial cell migration [IMP]
- cytokinesis [IMP]
- integrin-mediated signaling pathway [NAS]
- leukocyte migration [NAS]
- membrane protein ectodomain proteolysis [IDA]
- monocyte differentiation [IEP]
- platelet aggregation [IMP]
- platelet formation [IMP]
- protein transport [IMP]
- regulation of cell shape [IMP]
Gene Ontology Molecular Function- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity [IDA]
- actin binding [IDA]
- actin filament binding [IDA, NAS]
- actin-dependent ATPase activity [IDA]
- microfilament motor activity [IDA]
- motor activity [NAS]
- poly(A) RNA binding [IDA]
- protein anchor [IMP]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity [IDA]
- actin binding [IDA]
- actin filament binding [IDA, NAS]
- actin-dependent ATPase activity [IDA]
- microfilament motor activity [IDA]
- motor activity [NAS]
- poly(A) RNA binding [IDA]
- protein anchor [IMP]
- protein binding [IPI]
- protein homodimerization activity [IDA]
Gene Ontology Cellular Component
- COP9 signalosome [IDA]
- actin cytoskeleton [IDA]
- actomyosin [IDA]
- actomyosin contractile ring [IDA]
- cell leading edge [IDA]
- cleavage furrow [IDA]
- cytoplasm [IDA]
- cytosol [IDA]
- extracellular vesicular exosome [IDA]
- immunological synapse [IDA]
- integrin complex [IDA]
- membrane [IDA]
- myosin II complex [IDA]
- myosin II filament [IDA]
- nucleus [IDA]
- plasma membrane [IDA]
- protein complex [IDA]
- ruffle [IDA]
- stress fiber [IDA]
- uropod [IDA]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.363493008 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.363493008046993, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
ANLN MYH9 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
ANLN MYH9 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
ANLN MYH9 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 1445544 |
Curated By
- BioGRID