HYAL1
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- cartilage development [IEP]
- cellular response to UV-B [IDA]
- cellular response to fibroblast growth factor stimulus [IDA]
- cellular response to interleukin-1 [IDA]
- cellular response to pH [IDA]
- cellular response to platelet-derived growth factor stimulus [IDA]
- cellular response to tumor necrosis factor [IEP]
- chondroitin sulfate catabolic process [TAS]
- chondroitin sulfate metabolic process [TAS]
- glycosaminoglycan metabolic process [TAS]
- hyaluronan biosynthetic process [IDA]
- hyaluronan catabolic process [IDA, TAS]
- hyaluronan metabolic process [IDA, TAS]
- inflammatory response [IDA]
- negative regulation of cell growth [IDA]
- positive regulation of angiogenesis [IDA, IMP]
- positive regulation of cell adhesion [IMP]
- positive regulation of cell growth [IMP]
- positive regulation of epithelial cell migration [IDA]
- positive regulation of epithelial cell proliferation [IDA]
- positive regulation of growth [IDA]
- positive regulation of hyaluranon cable assembly [IDA]
- response to antibiotic [IDA]
- response to reactive oxygen species [IDA]
- response to virus [IDA]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CANX
Gene Ontology Biological Process
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- cellular protein metabolic process [TAS]
- clathrin-mediated endocytosis [ISS]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
- protein folding [TAS]
- protein secretion [TAS]
- synaptic vesicle endocytosis [ISS]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.619118342 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.619118341794461, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HYAL1 CANX | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8803 | BioGRID | 3129586 |
Curated By
- BioGRID