BAIT
AVPR2
ADHR, DI1, DIR, DIR3, NDI, V2R
arginine vasopressin receptor 2
GO Process (12)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- activation of adenylate cyclase activity [TAS]
- adenylate cyclase-modulating G-protein coupled receptor signaling pathway [TAS]
- cellular response to hormone stimulus [IBA]
- excretion [TAS]
- hemostasis [TAS]
- positive regulation of gene expression [ISS]
- positive regulation of protein ubiquitination [NAS]
- positive regulation of vasoconstriction [IBA]
- regulation of systemic arterial blood pressure by vasopressin [IBA]
- response to peptide [IBA]
- transmembrane transport [TAS]
- water transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RAB38
NY-MEL-1, rrGTPbp
RAB38, member RAS oncogene family
GO Process (9)
GO Function (9)
GO Component (6)
Gene Ontology Biological Process
- GTP catabolic process [IBA]
- Rab protein signal transduction [IBA]
- endosome to melanosome transport [IMP]
- intracellular protein transport [IBA]
- melanosome assembly [IMP]
- phagosome acidification [IMP]
- protein localization to membrane [IMP]
- protein transport [NAS]
- small GTPase mediated signal transduction [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Status: Pre-Publication Dataset
Quantitative Score
- 0.982828736 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.982828736244201, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Curated By
- BioGRID