ALOX15
Gene Ontology Biological Process
- apoptotic cell clearance [ISS]
- arachidonic acid metabolic process [IDA, NAS, TAS]
- bone mineralization [ISS]
- cellular response to calcium ion [IDA]
- cellular response to interleukin-13 [IMP]
- hepoxilin biosynthetic process [ISS]
- inflammatory response [TAS]
- leukotriene metabolic process [TAS]
- lipoxin A4 biosynthetic process [ISS]
- lipoxygenase pathway [IDA, TAS]
- negative regulation of adaptive immune response [ISS]
- ossification [ISS]
- phosphatidylethanolamine biosynthetic process [ISS]
- positive regulation of ERK1 and ERK2 cascade [IMP]
- positive regulation of actin filament polymerization [ISS]
- positive regulation of cell-substrate adhesion [IDA]
- regulation of engulfment of apoptotic cell [ISS]
- regulation of peroxisome proliferator activated receptor signaling pathway [ISS]
- response to endoplasmic reticulum stress [ISS]
- small molecule metabolic process [TAS]
- wound healing [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
DCAF10
Gene Ontology Biological Process
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.543590914 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.543590914200957, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ALOX15 DCAF10 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.7526 | BioGRID | 3027677 |
Curated By
- BioGRID