ANTP
Gene Ontology Biological Process
- anterior/posterior axis specification [IMP]
- heart development [IEP]
- lymph gland development [IMP]
- midgut development [TAS]
- muscle cell fate specification [IMP]
- neuroblast development [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of transcription from RNA polymerase II promoter [NAS]
- segment specification [NAS]
- specification of segmental identity, antennal segment [IMP]
- specification of segmental identity, thorax [IMP]
Gene Ontology Molecular Function
NPA3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Systematic Screening of Penetratin's Protein Targets by Yeast Proteome Microarrays.
Cell-penetrating peptides (CPPs) have distinct properties to translocate across cell envelope. The key property of CPPs to translocation with attached molecules has been utilized as vehicles for the delivery of several potential drug candidates that illustrate the significant effect in in-vitro experiment but fail in in-vivo experiment due to selectively permeable nature of cell envelop. Penetratin, a well-known CPP identified ... [more]
Throughput
- Low Throughput
Additional Notes
- Proteome Microarrays
Curated By
- BioGRID