BAIT

CRM1

KAP124, XPO1, exportin CRM1, L000000420, YGR218W
Major karyopherin; involved in export of proteins, RNAs, and ribosomal subunits from the nucleus; exportin
Saccharomyces cerevisiae (S288c)
PREY

SGM1

YJR134C
Protein of unknown function; required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus
GO Process (0)
GO Function (0)
GO Component (2)

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Nuclear export receptor Xpo1/Crm1 is physically and functionally linked to the spindle pole body in budding yeast.

Neuber A, Franke J, Wittstruck A, Schlenstedt G, Sommer T, Stade K

The spindle pole body (SPB) represents the microtubule organizing center in the budding yeast Saccharomyces cerevisiae. It is a highly structured organelle embedded in the nuclear membrane, which is required to anchor microtubules on both sides of the nuclear envelope. The protein Spc72, a component of the SPB, is located at the cytoplasmic face of this organelle and serves as ... [more]

Mol. Cell. Biol. Sep. 01, 2008; 28(17);5348-58 [Pubmed: 18573877]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
CRM1 SGM1
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
-

Curated By

  • BioGRID