BAIT
PAX8
paired box 8
GO Process (33)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
- anatomical structure morphogenesis [TAS]
- branching involved in ureteric bud morphogenesis [IEP]
- cellular response to gonadotropin stimulus [IDA]
- central nervous system development [IEP]
- inner ear morphogenesis [ISS]
- kidney development [IEP]
- mesenchymal to epithelial transition involved in metanephros morphogenesis [IEP]
- mesonephros development [ISS]
- metanephric S-shaped body morphogenesis [IEP]
- metanephric comma-shaped body morphogenesis [IEP]
- metanephric distal convoluted tubule development [ISS]
- metanephric epithelium development [IEP]
- metanephric nephron tubule formation [ISS]
- negative regulation of apoptotic process involved in metanephric collecting duct development [ISS]
- negative regulation of apoptotic process involved in metanephric nephron tubule development [ISS]
- negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis [ISS]
- negative regulation of mesenchymal cell apoptotic process involved in metanephros development [ISS]
- otic vesicle development [IEP]
- positive regulation of branching involved in ureteric bud morphogenesis [ISS]
- positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [ISS]
- positive regulation of metanephric DCT cell differentiation [ISS]
- positive regulation of thyroid hormone generation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA, ISS]
- pronephric field specification [ISS]
- pronephros development [ISS]
- regulation of apoptotic process [ISS]
- regulation of metanephric nephron tubule epithelial cell differentiation [ISS]
- regulation of thyroid-stimulating hormone secretion [IMP]
- thyroid gland development [IEP, IMP]
- thyroid-stimulating hormone signaling pathway [TAS]
- transcription, DNA-templated [IDA]
- urogenital system development [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA, ISS]
- nucleus [IDA]
Homo sapiens
PREY
CIT
CRIK, STK21
citron rho-interacting serine/threonine kinase
GO Process (4)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- Filtered using SAINT software tools (cutoff 0.74) and CRAPome database
Curated By
- BioGRID