BAIT
PIGR
polymeric immunoglobulin receptor
GO Process (6)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
- Fc receptor signaling pathway [IDA]
- detection of chemical stimulus involved in sensory perception of bitter taste [IDA]
- epidermal growth factor receptor signaling pathway [IDA]
- immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [IDA]
- receptor clustering [IDA]
- retina homeostasis [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PRDX1
MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, RP11-291L19.4
peroxiredoxin 1
GO Process (3)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.
Polymeric immunoglobulin receptor (pIgR)-mediated polymeric immunoglobulin A (pIgA) transcytosis across mucosal epithelial cells plays an essential role in mucosal immunity. The general trafficking process has been well investigated, yet the elaborate regulatory mechanisms remain enigmatic. We identified a new pIgR interacting protein, the Rab11 effector Rab11-FIP1. Rab11-FIP1 and Rab11-FIP5 knockdown additively impaired pIgA transcytosis in both polarized and incompletely polarized ... [more]
Int J Mol Sci Sep. 28, 2021; 22(19); [Pubmed: 34638806]
Throughput
- Low Throughput
Curated By
- BioGRID