BAIT
PIGR
polymeric immunoglobulin receptor
GO Process (6)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
- Fc receptor signaling pathway [IDA]
- detection of chemical stimulus involved in sensory perception of bitter taste [IDA]
- epidermal growth factor receptor signaling pathway [IDA]
- immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [IDA]
- receptor clustering [IDA]
- retina homeostasis [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TUFM
COXPD4, EF-TuMT, EFTU, P43
Tu translation elongation factor, mitochondrial
GO Process (1)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.
Polymeric immunoglobulin receptor (pIgR)-mediated polymeric immunoglobulin A (pIgA) transcytosis across mucosal epithelial cells plays an essential role in mucosal immunity. The general trafficking process has been well investigated, yet the elaborate regulatory mechanisms remain enigmatic. We identified a new pIgR interacting protein, the Rab11 effector Rab11-FIP1. Rab11-FIP1 and Rab11-FIP5 knockdown additively impaired pIgA transcytosis in both polarized and incompletely polarized ... [more]
Int J Mol Sci Sep. 28, 2021; 22(19); [Pubmed: 34638806]
Throughput
- Low Throughput
Curated By
- BioGRID