CANX
Gene Ontology Biological Process
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- cellular protein metabolic process [TAS]
- clathrin-mediated endocytosis [ISS]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
- protein folding [TAS]
- protein secretion [TAS]
- synaptic vesicle endocytosis [ISS]
Gene Ontology Molecular Function
SCARB1
Gene Ontology Biological Process
- adhesion of symbiont to host [IMP]
- cholesterol efflux [ISS]
- cholesterol homeostasis [ISS]
- cholesterol import [ISS]
- detection of lipopolysaccharide [IDA]
- high-density lipoprotein particle clearance [IDA]
- high-density lipoprotein particle remodeling [ISS]
- lipopolysaccharide transport [IDA]
- lipopolysaccharide-mediated signaling pathway [IDA]
- lipoprotein metabolic process [TAS]
- low-density lipoprotein particle clearance [ISS]
- phospholipid transport [ISS]
- positive regulation of cholesterol storage [IDA]
- positive regulation of endothelial cell migration [TAS]
- positive regulation of nitric-oxide synthase activity [IDA]
- positive regulation of triglyceride biosynthetic process [ISS]
- receptor-mediated endocytosis [IDA]
- recognition of apoptotic cell [IDA]
- regulation of phagocytosis [IC]
- regulation of phosphatidylcholine catabolic process [ISS]
- reverse cholesterol transport [IEP]
- small molecule metabolic process [TAS]
- triglyceride homeostasis [ISS]
- wound healing [TAS]
Gene Ontology Molecular Function- 1-phosphatidylinositol binding [TAS]
- apolipoprotein A-I binding [IPI]
- apolipoprotein binding [IPI]
- high-density lipoprotein particle receptor activity [IDA]
- lipopolysaccharide binding [IDA]
- lipopolysaccharide receptor activity [IDA]
- low-density lipoprotein particle binding [IDA]
- phosphatidylserine binding [ISS]
- protein binding [IPI]
- transporter activity [TAS]
- 1-phosphatidylinositol binding [TAS]
- apolipoprotein A-I binding [IPI]
- apolipoprotein binding [IPI]
- high-density lipoprotein particle receptor activity [IDA]
- lipopolysaccharide binding [IDA]
- lipopolysaccharide receptor activity [IDA]
- low-density lipoprotein particle binding [IDA]
- phosphatidylserine binding [ISS]
- protein binding [IPI]
- transporter activity [TAS]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Elucidating the wiring diagram of the human cell is a central goal of the postgenomic era. We combined genome engineering, confocal live-cell imaging, mass spectrometry, and data science to systematically map the localization and interactions of human proteins. Our approach provides a data-driven description of the molecular and spatial networks that organize the proteome. Unsupervised clustering of these networks delineates ... [more]
Throughput
- High Throughput
Additional Notes
- Bait generated from library of CRISPR-edited human embryonic kidney (HEK) 293T cell lines harboring fluorescent tags on individual proteins
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CANX SCARB1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID