BAIT
CHD7
CRG, HH5, IS3, KAL5
chromodomain helicase DNA binding protein 7
GO Process (16)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- T cell differentiation [IMP]
- central nervous system development [IMP]
- cognition [IMP]
- cranial nerve development [IMP]
- face development [IMP]
- genitalia development [IMP]
- heart morphogenesis [IMP]
- in utero embryonic development [IMP]
- inner ear morphogenesis [IMP]
- limb development [IMP]
- nose development [IMP]
- palate development [IMP]
- regulation of growth hormone secretion [IMP]
- regulation of transcription, DNA-templated [NAS]
- retina development in camera-type eye [IMP]
- skeletal system development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA]
- nucleus [IDA, TAS]
Homo sapiens
PREY
CTCF
MRD21
CCCTC-binding factor (zinc finger protein)
GO Process (8)
GO Function (9)
GO Component (5)
Gene Ontology Biological Process
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- nucleosome positioning [IDA]
- positive regulation of gene expression [IMP]
- positive regulation of transcription, DNA-templated [IDA, IMP]
- regulation of centromeric sister chromatid cohesion [NAS]
- regulation of gene expression, epigenetic [IMP]
- regulation of molecular function, epigenetic [IMP]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- chromatin insulator sequence binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription corepressor activity [TAS]
- transcription regulatory region DNA binding [IDA]
- zinc ion binding [TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- chromatin insulator sequence binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription corepressor activity [TAS]
- transcription regulatory region DNA binding [IDA]
- zinc ion binding [TAS]
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Solution structure of the BRK domains from CHD7.
CHD7 is a member of the chromodomain helicase DNA binding domain (CHD) family of ATP-dependent chromatin remodelling enzymes. It is mutated in CHARGE syndrome, a multiple congenital anomaly condition. CHD7 is one of a subset of CHD proteins, unique to metazoans that contain the BRK domain, a protein module also found in the Brahma/BRG1 family of helicases. We describe here ... [more]
J. Mol. Biol. Aug. 31, 2007; 371(5);1135-40 [Pubmed: 17603073]
Throughput
- Low Throughput
Curated By
- BioGRID