BAIT

ACOT7

ACH1, ACT, BACH, CTE-II, LACH, LACH1, hBACH, RP1-120G22.10

acyl-CoA thioesterase 7

Arachidonic Acid Pathway Project

GO Process (5)

GO Function (5)

GO Component (4)

Gene Ontology Biological Process

coenzyme A biosynthetic process [IDA]

long-chain fatty-acyl-CoA catabolic process [IDA]

medium-chain fatty acid biosynthetic process [IDA]

medium-chain fatty-acyl-CoA catabolic process [IDA]

palmitic acid biosynthetic process [IDA]

Gene Ontology Molecular Function

fatty-acyl-CoA binding [IDA]
long-chain fatty acyl-CoA binding [IDA]
palmitoyl-CoA hydrolase activity [IDA]
protein binding [IPI]
protein homodimerization activity [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

extracellular vesicular exosome [IDA]

nucleoplasm [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

PREY

KDM7A

JHDM1D

lysine (K)-specific demethylase 7A

Synthetic Protein Interaction Project

GO Process (5)

GO Function (8)

GO Component (3)

Gene Ontology Biological Process

histone H3-K27 demethylation [IDA]

histone H3-K36 demethylation [IDA]

histone H3-K9 demethylation [IDA]

histone H4-K20 demethylation [IDA]

midbrain development [ISS]

Gene Ontology Molecular Function

histone demethylase activity (H3-K27 specific) [IDA]
histone demethylase activity (H3-K36 specific) [IDA]
histone demethylase activity (H3-K9 specific) [IDA]
histone demethylase activity (H4-K20 specific) [IDA]
iron ion binding [IDA, TAS]
methylated histone binding [IDA]
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [IDA]
zinc ion binding [IDA]

Gene Ontology Cellular Component

nucleolus [IDA]

nucleoplasm [IDA]

CRISPR Database HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia.

Ciardullo C, Szoltysek K, Zhou P, Pietrowska M, Marczak L, Willmore E, Enshaei A, Walaszczyk A, Ho JY, Rand V, Marshall S, Hall AG, Harrison CJ, Soundararajan M, Eswaran J

Chronic lymphocytic leukaemia (CLL) is a heterogeneous disease with a highly variable clinical outcome. There are well-established CLL prognostic biomarkers that have transformed treatment and improved the understanding of CLL biology. Here, we have studied the clinical significance of two crucial B cell regulators, BACH2 (BTB and CNC homology 1, basic leucine zipper transcription factor 2) and BCL6 (B-cell CLL/lymphoma ... [more]

Cancers (Basel) Dec. 21, 2021; 14(1); [Pubmed: 35008187]

Throughput

Low Throughput

Curated By

BioGRID