An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia.

Ciardullo C, Szoltysek K, Zhou P, Pietrowska M, Marczak L, Willmore E, Enshaei A, Walaszczyk A, Ho JY, Rand V, Marshall S, Hall AG, Harrison CJ, Soundararajan M, Eswaran J

Chronic lymphocytic leukaemia (CLL) is a heterogeneous disease with a highly variable clinical outcome. There are well-established CLL prognostic biomarkers that have transformed treatment and improved the understanding of CLL biology. Here, we have studied the clinical significance of two crucial B cell regulators, BACH2 (BTB and CNC homology 1, basic leucine zipper transcription factor 2) and BCL6 (B-cell CLL/lymphoma ... [more]

Cancers (Basel) Dec. 21, 2021; 14(1); [Pubmed: 35008187]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
ACOT7 PPA1	Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.	Havugimana PC (2022)	High	-	BioGRID	3429577

Curated By

BioGRID

Interaction Summary

ACOT7

Gene Ontology Biological Process

Gene Ontology Molecular Function

fatty-acyl-CoA binding [IDA]long-chain fatty acyl-CoA binding [IDA]palmitoyl-CoA hydrolase activity [IDA]protein binding [IPI]protein homodimerization activity [IPI]

Gene Ontology Cellular Component

PPA1