An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia.

Ciardullo C, Szoltysek K, Zhou P, Pietrowska M, Marczak L, Willmore E, Enshaei A, Walaszczyk A, Ho JY, Rand V, Marshall S, Hall AG, Harrison CJ, Soundararajan M, Eswaran J

Chronic lymphocytic leukaemia (CLL) is a heterogeneous disease with a highly variable clinical outcome. There are well-established CLL prognostic biomarkers that have transformed treatment and improved the understanding of CLL biology. Here, we have studied the clinical significance of two crucial B cell regulators, BACH2 (BTB and CNC homology 1, basic leucine zipper transcription factor 2) and BCL6 (B-cell CLL/lymphoma ... [more]

Cancers (Basel) Dec. 21, 2021; 14(1); [Pubmed: 35008187]

Throughput

Low Throughput

Curated By

BioGRID

Interaction Summary

ACOT7

Gene Ontology Biological Process

Gene Ontology Molecular Function

fatty-acyl-CoA binding [IDA]long-chain fatty acyl-CoA binding [IDA]palmitoyl-CoA hydrolase activity [IDA]protein binding [IPI]protein homodimerization activity [IPI]

Gene Ontology Cellular Component

RPN1

Gene Ontology Biological Process

Gene Ontology Molecular Function

dolichyl-diphosphooligosaccharide-protein glycotransferase activity [TAS]poly(A) RNA binding [IDA]protein binding [IPI]

Gene Ontology Cellular Component

Affinity Capture-MS

Publication

Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia.

Throughput

Curated By

fatty-acyl-CoA binding [IDA]
long-chain fatty acyl-CoA binding [IDA]
palmitoyl-CoA hydrolase activity [IDA]
protein binding [IPI]
protein homodimerization activity [IPI]

dolichyl-diphosphooligosaccharide-protein glycotransferase activity [TAS]
poly(A) RNA binding [IDA]
protein binding [IPI]