SNX3
Gene Ontology Biological Process
- intralumenal vesicle formation [IMP]
- membrane invagination [IDA]
- negative regulation of early endosome to late endosome transport [IDA]
- negative regulation of phagocytosis [IMP]
- negative regulation of protein catabolic process [IDA]
- negative regulation of protein transport [IDA]
- negative regulation of viral entry into host cell [IDA]
- positive regulation of neuron projection development [ISS]
- protein to membrane docking [IDA]
- regulation of Wnt signaling pathway [IMP]
- response to bacterium [IDA]
- vesicle organization [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
AKR1A1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MDA231 cell line (score 0.631)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SNX3 AKR1A1 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.4598 | BioGRID | 1258375 |
Curated By
- BioGRID