BAIT
CTSB
APPS, CPSB
cathepsin B
GO Process (10)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- cellular response to thyroid hormone stimulus [IEP]
- collagen catabolic process [IDA, TAS]
- epithelial cell differentiation [IEP]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- innate immune response [TAS]
- proteolysis [IDA]
- proteolysis involved in cellular protein catabolic process [IDA]
- regulation of apoptotic process [TAS]
- toll-like receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
AASDHPPT
AASD-PPT, LYS2, LYS5, CGI-80
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
GO Process (4)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.71)
Curated By
- BioGRID