BAIT
LAMC1
LAMB2, RP11-181K3.1
laminin, gamma 1 (formerly LAMB2)
GO Process (10)
GO Function (1)
GO Component (8)
Gene Ontology Biological Process
- axon guidance [TAS]
- cell adhesion [IDA]
- cell migration [IMP]
- endoderm development [TAS]
- extracellular matrix disassembly [IMP, TAS]
- extracellular matrix organization [TAS]
- hemidesmosome assembly [IMP]
- positive regulation of epithelial cell proliferation [TAS]
- protein complex assembly [IDA]
- substrate adhesion-dependent cell spreading [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ITGB4
CD104
integrin, beta 4
GO Process (14)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- amelogenesis [IMP]
- autophagy [IMP]
- cell adhesion [NAS]
- cell junction assembly [TAS]
- cell motility [IMP]
- cell-matrix adhesion [IMP]
- digestive tract development [IMP]
- extracellular matrix organization [TAS]
- hemidesmosome assembly [IDA, IMP, TAS]
- mesodermal cell differentiation [IEP]
- nail development [IMP]
- renal system development [IMP]
- response to wounding [IDA]
- skin development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF10A cell line (score 0.686)
- MCF7 cell line (score 0.71)
- MDA231 cell line (score 0.659)
Curated By
- BioGRID