BAIT
EPHX2
CEH, SEH
epoxide hydrolase 2, cytoplasmic
GO Process (17)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- arachidonic acid metabolic process [TAS]
- cellular calcium ion homeostasis [NAS]
- cholesterol homeostasis [IDA]
- dephosphorylation [IDA]
- drug metabolic process [NAS]
- epoxygenase P450 pathway [TAS]
- inflammatory response [NAS]
- phospholipid dephosphorylation [IDA]
- positive regulation of gene expression [IDA]
- positive regulation of vasodilation [NAS]
- reactive oxygen species metabolic process [NAS]
- regulation of blood pressure [NAS]
- regulation of cholesterol metabolic process [IMP]
- response to toxic substance [NAS]
- small molecule metabolic process [TAS]
- stilbene catabolic process [IDA]
- xenobiotic metabolic process [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FKBP4
FKBP51, FKBP52, FKBP59, HBI, Hsp56, PPIase, p52
FK506 binding protein 4, 59kDa
GO Process (5)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MCF7 cell line (score 0.628)
Curated By
- BioGRID