BAIT
RPS14
EMTB, S14, PRO2640
ribosomal protein S14
GO Process (18)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- erythrocyte differentiation [IMP]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- maturation of SSU-rRNA [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- regulation of translation [IMP]
- ribosomal small subunit assembly [IMP, ISS]
- translation [IC, IMP, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
EIF5A
EIF-5A, EIF5A1, eIF5AI
eukaryotic translation initiation factor 5A
GO Process (9)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- apoptotic process [IDA]
- cellular protein metabolic process [TAS]
- mRNA export from nucleus [IMP]
- nucleocytoplasmic transport [IDA, IMP]
- peptidyl-lysine modification to peptidyl-hypusine [TAS]
- positive regulation of cell proliferation [IGI]
- positive regulation of translational elongation [ISS]
- post-translational protein modification [TAS]
- protein export from nucleus [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.
Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reproducible multiplex CF/MS (mCF/MS) platform for measuring and comparing, simultaneously, multi-protein assemblies across different experimental samples at a rate that is up to an order ... [more]
Nat Commun Jul. 13, 2022; 13(1);4043 [Pubmed: 35831314]
Throughput
- High Throughput
Additional Notes
- High confidence interactions were identified as having an EPIC score >=0.625 in applicable cell lines (MCF7, MDA231 or MCF10A)
- MDA231 cell line (score 0.649)
Curated By
- BioGRID