BAIT
AATF
BFR2, CHE-1, CHE1, DED, HSPC277
apoptosis antagonizing transcription factor
GO Process (8)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- apoptotic signaling pathway [TAS]
- cellular response to DNA damage stimulus [IEP]
- negative regulation of apoptotic process [IMP]
- negative regulation of reactive oxygen species metabolic process [IDA]
- negative regulation of superoxide anion generation [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of apoptotic process [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KIF2A
CDCBM3, HK2, KIF2
kinesin heavy chain member 2A
GO Process (9)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- blood coagulation [TAS]
- metabolic process [IBA, TAS]
- microtubule depolymerization [IBA]
- microtubule-based movement [IBA, TAS]
- mitotic cell cycle [TAS]
- mitotic spindle organization [IDA]
- spindle assembly involved in mitosis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.
AATF is a central regulator of the cellular outcome upon p53 activation, a finding that has primarily been attributed to its function as a transcription factor. Recent data showed that AATF is essential for ribosome biogenesis and plays a role in rRNA maturation. AATF has been implicated to fulfil this role through direct interaction with rRNA and was identified in ... [more]
Sci Rep Dec. 30, 2018; 9(1);11071 [Pubmed: 31363146]
Throughput
- High Throughput
Curated By
- BioGRID