BAIT
CSNK2A2
CK2A2, CSNK2A1
casein kinase 2, alpha prime polypeptide
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
TAF1B
MGC:9349, RAF1B, RAFI63, SL1, TAFI63
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
GO Process (7)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript [IDA]
- gene expression [TAS]
- termination of RNA polymerase I transcription [TAS]
- transcription elongation from RNA polymerase I promoter [TAS]
- transcription from RNA polymerase I promoter [TAS]
- transcription initiation from RNA polymerase I promoter [TAS]
- transcription, DNA-templated [NAS]
Gene Ontology Molecular Function- RNA polymerase I CORE element sequence-specific DNA binding [IDA]
- RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity [IDA]
- TBP-class protein binding [TAS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- RNA polymerase I CORE element sequence-specific DNA binding [IDA]
- RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity [IDA]
- TBP-class protein binding [TAS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
Protein kinases are essential for signal transduction and control of most cellular processes, including metabolism, membrane transport, motility, and cell cycle. Despite the critical role of kinases in cells and their strong association with diseases, good coverage of their interactions is available for only a fraction of the 535 human kinases. Here, we present a comprehensive mass-spectrometry-based analysis of a ... [more]
Mol Cell Dec. 06, 2019; 79(3);504-520.e9 [Pubmed: 32707033]
Quantitative Score
- 102.0 [Protein Abundance Ratio]
Throughput
- High Throughput
Additional Notes
- Affinity Capture-MS was carried out to identify high confidence protein-protein interactors with a FDR<1% (protein abundance ratio compared to control are reported)
Curated By
- BioGRID