BAIT
PRKX
PKX1
protein kinase, X-linked
GO Process (13)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- angiogenesis [IMP]
- cell adhesion [IMP]
- cell-substrate adhesion [IMP]
- endothelial cell migration [IMP]
- endothelial cell proliferation [IMP]
- epithelial tube morphogenesis [IDA]
- kidney morphogenesis [IDA]
- myeloid cell differentiation [IDA]
- peptidyl-serine phosphorylation [IDA]
- protein autophosphorylation [IDA]
- regulation of cell adhesion [IDA]
- regulation of cell migration [IDA]
- regulation of epithelial cell differentiation involved in kidney development [IDA]
Gene Ontology Molecular Function
Homo sapiens
PREY
AIP
ARA9, FKBP16, FKBP37, SMTPHN, XAP-2, XAP2
aryl hydrocarbon receptor interacting protein
GO Process (4)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
Protein kinases are essential for signal transduction and control of most cellular processes, including metabolism, membrane transport, motility, and cell cycle. Despite the critical role of kinases in cells and their strong association with diseases, good coverage of their interactions is available for only a fraction of the 535 human kinases. Here, we present a comprehensive mass-spectrometry-based analysis of a ... [more]
Mol Cell Dec. 06, 2019; 79(3);504-520.e9 [Pubmed: 32707033]
Quantitative Score
- 170.0 [Protein Abundance Ratio]
Throughput
- High Throughput
Additional Notes
- Affinity Capture-MS was carried out to identify high confidence protein-protein interactors with a FDR<1% (protein abundance ratio compared to control are reported)
Curated By
- BioGRID