BAIT
CAMK4
CaMK IV, CaMK-GR, IV, caMK
calcium/calmodulin-dependent protein kinase IV
GO Process (13)
GO Function (0)
GO Component (4)
Gene Ontology Biological Process
- activation of phospholipase C activity [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- long-term memory [IGI]
- myeloid dendritic cell cytokine production [IMP]
- myeloid dendritic cell differentiation [IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of T cell differentiation in thymus [TAS]
- regulation of osteoclast differentiation [TAS]
- signal transduction [TAS]
- synaptic transmission [TAS]
Gene Ontology Cellular Component
Homo sapiens
PREY
GNB1
RP1-283E3.7
guanine nucleotide binding protein (G protein), beta polypeptide 1
GO Process (16)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- G-protein coupled acetylcholine receptor signaling pathway [TAS]
- GTP catabolic process [IDA, TAS]
- Ras protein signal transduction [TAS]
- adenylate cyclase-activating dopamine receptor signaling pathway [ISS]
- blood coagulation [TAS]
- cellular response to catecholamine stimulus [ISS]
- cellular response to glucagon stimulus [TAS]
- cellular response to prostaglandin E stimulus [ISS]
- energy reserve metabolic process [TAS]
- phototransduction, visible light [TAS]
- platelet activation [TAS]
- regulation of rhodopsin mediated signaling pathway [TAS]
- rhodopsin mediated signaling pathway [TAS]
- signal transduction [TAS]
- small molecule metabolic process [TAS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
Protein kinases are essential for signal transduction and control of most cellular processes, including metabolism, membrane transport, motility, and cell cycle. Despite the critical role of kinases in cells and their strong association with diseases, good coverage of their interactions is available for only a fraction of the 535 human kinases. Here, we present a comprehensive mass-spectrometry-based analysis of a ... [more]
Mol Cell Dec. 06, 2019; 79(3);504-520.e9 [Pubmed: 32707033]
Quantitative Score
- 204.0 [Protein Abundance Ratio]
Throughput
- High Throughput
Additional Notes
- Affinity Capture-MS was carried out to identify high confidence protein-protein interactors with a FDR<1% (protein abundance ratio compared to control are reported)
Curated By
- BioGRID