BAIT
PKDCC
SGK493, Vlk
protein kinase domain containing, cytoplasmic
GO Process (7)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- embryonic digestive tract development [ISS]
- lung alveolus development [ISS]
- negative regulation of Golgi to plasma membrane protein transport [ISS]
- palate development [ISS]
- peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of bone mineralization [ISS]
- positive regulation of chondrocyte differentiation [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CCT5
CCT-epsilon, CCTE, HEL-S-69, TCP-1-epsilon
chaperonin containing TCP1, subunit 5 (epsilon)
GO Process (4)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
Protein kinases are essential for signal transduction and control of most cellular processes, including metabolism, membrane transport, motility, and cell cycle. Despite the critical role of kinases in cells and their strong association with diseases, good coverage of their interactions is available for only a fraction of the 535 human kinases. Here, we present a comprehensive mass-spectrometry-based analysis of a ... [more]
Mol Cell Dec. 06, 2019; 79(3);504-520.e9 [Pubmed: 32707033]
Quantitative Score
- 147.826087 [Protein Abundance Ratio]
Throughput
- High Throughput
Additional Notes
- Affinity Capture-MS was carried out to identify high confidence protein-protein interactors with a FDR<1% (protein abundance ratio compared to control are reported)
Curated By
- BioGRID