BAIT
NSP14
ORF1ab, ORF1ab-nsp14, SARS-CoV2 nsp14, SARS-CoV-2 nsp14, Guanine-N7 methyltransferase, exonuclease, R1AB_SARS2, PRO_0000449631, GU280_gp01_nsp14
Guanine-N7 methyltransferase; Non-structural protein 14; 3-to-5 exonuclease
GO Process (0)
GO Function (0)
GO Component (0)
Severe acute respiratory syndrome coronavirus 2
PREY
ABLIM1
ABLIM, LIMAB1, LIMATIN, abLIM-1, RP11-317F20.1
actin binding LIM protein 1
GO Process (5)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.
The global epidemic caused by the coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has resulted in the infection of over 200 million people. To extend the knowledge of interactions between SARS-CoV-2 and humans, we systematically investigate the interactome of 29 viral proteins in human cells by using an antibody-based TurboID assay. In total, 1,388 high-confidence human proximal proteins with biotinylated ... [more]
Cell Chem Biol Dec. 20, 2021; 29(1);5-18.e6 [Pubmed: 34672954]
Throughput
- High Throughput
Additional Notes
- BioID
- High confidence SARS-CoV-2 viral and human protein interactions were identified in HEK293T cells using the TurboID proximity labeling method.
- TurboID
Curated By
- BioGRID