BAIT
CCNF
FBX1, FBXO1
cyclin F
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
ACOT8
HNAACTE, PTE-1, PTE-2, PTE1, PTE2, hACTE-III, hTE, RP3-337O18.2
acyl-CoA thioesterase 8
GO Process (10)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
- acyl-CoA metabolic process [IDA]
- alpha-linolenic acid metabolic process [TAS]
- bile acid biosynthetic process [TAS]
- bile acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- dicarboxylic acid catabolic process [IDA]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- peroxisome fission [IDA]
- small molecule metabolic process [TAS]
- unsaturated fatty acid metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- peroxisomal matrix [IDA, IMP, TAS]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
ALS-linked loss of Cyclin-F function affects HSP90.
The founding member of the F-box protein family, Cyclin-F, serves as a substrate adaptor for the E3 ligase Skp1-Cul1-F-box (SCF)<sup>Cyclin-F</sup> which is responsible for ubiquitination of proteins involved in cell cycle progression, DNA damage and mitotic fidelity. Missense mutations in <i>CCNF</i> encoding for Cyclin-F are associated with amyotrophic lateral sclerosis (ALS). However, it remains elusive whether <i>CCNF</i> mutations affect the ... [more]
Life Sci Alliance Sep. 16, 2022; 5(12); [Pubmed: 36114006]
Throughput
- High Throughput
Curated By
- BioGRID