GPR1
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IMP, IPI]
- detection of glucose [IMP]
- detection of sucrose stimulus [IMP]
- glucose mediated signaling pathway [IGI, IMP]
- hexose mediated signaling [IGI, IMP]
- invasive growth in response to glucose limitation [IMP]
- pseudohyphal growth [IMP]
- replicative cell aging [IMP]
- sucrose mediated signaling [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SCH9
Gene Ontology Biological Process
- age-dependent response to oxidative stress involved in chronological cell aging [IMP]
- positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription from RNA polymerase I promoter [IGI, IMP]
- positive regulation of transcription from RNA polymerase III promoter [IGI, IMP]
- protein phosphorylation [IMP]
- regulation of cell size [IMP]
- regulation of protein localization [IMP]
- regulation of response to osmotic stress [IMP]
- regulation of sphingolipid biosynthetic process [IMP]
- regulation of transcription from RNA polymerase II promoter in response to oxidative stress [IMP]
- replicative cell aging [IMP]
Gene Ontology Molecular Function
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
Glucose regulates transcription in yeast through a network of signaling pathways.
Addition of glucose to yeast cells increases their growth rate and results in a massive restructuring of their transcriptional output. We have used microarray analysis in conjunction with conditional mutations to obtain a systems view of the signaling network responsible for glucose-induced transcriptional changes. We found that several well-studied signaling pathways-such as Snf1 and Rgt-are responsible for specialized but limited ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: rna accumulation (APO:0000224)
Additional Notes
- double mutants show global changes in gene regulation
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SCH9 GPR1 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 259031 |
Curated By
- BioGRID