BAIT
TRIM67
TNL
tripartite motif containing 67
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
GPX1
GPXD, GSHPX1
glutathione peroxidase 1
GO Process (21)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- UV protection [IMP]
- arachidonic acid metabolic process [TAS]
- cell redox homeostasis [IDA]
- cellular response to oxidative stress [NAS]
- glutathione metabolic process [IDA]
- heart contraction [IMP]
- hydrogen peroxide catabolic process [IDA]
- lipoxygenase pathway [TAS]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [IMP]
- negative regulation of release of cytochrome c from mitochondria [IMP]
- nucleobase-containing small molecule metabolic process [TAS]
- positive regulation of fibril organization [ISS]
- purine nucleobase metabolic process [TAS]
- purine nucleotide catabolic process [TAS]
- regulation of gene expression, epigenetic [IDA]
- regulation of mammary gland epithelial cell proliferation [IMP]
- regulation of proteasomal protein catabolic process [IDA]
- response to hydrogen peroxide [IMP]
- response to selenium ion [IMP]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing.
IDH mutant gliomas are grouped into astrocytomas or oligodendrogliomas depending on the co-deletion of chromosome arms 1p and 19q. Although the genomic alterations of IDH mutant gliomas have been well described, transcriptional changes unique to either tumor type have not been fully understood. Here, we identify Tripartite Motif Containing 67 (TRIM67), an E3 ubiquitin ligase with essential roles during neuronal ... [more]
Neuro Oncol Oct. 10, 2022; (); [Pubmed: 36215168]
Throughput
- High Throughput
Curated By
- BioGRID