BOWL
Gene Ontology Biological Process
- embryonic foregut morphogenesis [IMP]
- embryonic hindgut morphogenesis [IMP]
- hindgut morphogenesis [IMP]
- imaginal disc-derived leg joint morphogenesis [IMP]
- imaginal disc-derived leg morphogenesis [IMP]
- lateral inhibition [IMP]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- negative regulation of transcription, DNA-templated [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of transcription, DNA-templated [ISS]
- terminal region determination [IMP]
- wing disc development [IMP]
Gene Ontology Molecular Function
LIN
Gene Ontology Biological Process
- embryonic foregut morphogenesis [IMP]
- embryonic hindgut morphogenesis [IMP]
- embryonic pattern specification [IMP]
- epidermis development [IMP]
- foregut morphogenesis [IMP]
- hindgut morphogenesis [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- proximal/distal axis specification [IMP]
- spiracle morphogenesis, open tracheal system [IMP]
- terminal region determination [IGI]
- torso signaling pathway [IGI]
- wing disc development [IMP]
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| LIN BOWL | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | FlyBase | - | |
| BOWL LIN | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | FlyBase | - |
Curated By
- BioGRID