BAIT
FAM212B
C1orf183
family with sequence similarity 212, member B
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
CUL3
CUL-3, PHA2E
cullin 3
GO Process (20)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- COPII vesicle coating [IMP]
- ER to Golgi vesicle-mediated transport [IDA]
- G1/S transition of mitotic cell cycle [TAS]
- cell cycle arrest [TAS]
- cell migration [IMP]
- embryonic cleavage [ISS]
- integrin-mediated signaling pathway [ISS]
- intrinsic apoptotic signaling pathway [TAS]
- mitotic metaphase plate congression [IMP]
- negative regulation of Rho protein signal transduction [IMP]
- negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [IDA]
- positive regulation of cell proliferation [TAS]
- positive regulation of cytokinesis [IMP]
- positive regulation of mitotic metaphase/anaphase transition [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IDA]
- protein monoubiquitination [IDA]
- protein polyubiquitination [IDA]
- protein ubiquitination [IDA]
- stem cell division [ISS]
- stress fiber assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.
The p53 protein is a tumour suppressor and transcription factor that regulates the expression of target genes involved in numerous stress responses systems. In this study, we designed a screening strategy using DNA damage?induced mouse and human transcriptome data to identify novel downstream targets of p53. Our method selected genes with an induced expression in multiple organs of X?ray?irradiated p53 ... [more]
Int J Oncol Jun. 01, 2019; 54(6);1907-1920 [Pubmed: 31081062]
Throughput
- High Throughput
Curated By
- BioGRID