BAIT
CNPY3
CAG4A, ERDA5, PRAT4A, TNRC5, HSPC084
canopy FGF signaling regulator 3
GO Process (2)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
CYP1B1
CP1B, CYPIB1, GLC3A, P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1
GO Process (32)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- arachidonic acid metabolic process [IDA, TAS]
- blood vessel morphogenesis [ISS]
- cell adhesion [ISS]
- cellular response to hydrogen peroxide [ISS]
- cellular response to organic cyclic compound [IDA]
- collagen fibril organization [ISS]
- endothelial cell migration [ISS]
- epoxygenase P450 pathway [TAS]
- estrogen metabolic process [IDA]
- intrinsic apoptotic signaling pathway in response to oxidative stress [ISS]
- membrane lipid catabolic process [ISS]
- negative regulation of NF-kappaB transcription factor activity [ISS]
- negative regulation of cell adhesion mediated by integrin [ISS]
- negative regulation of cell migration [ISS]
- negative regulation of cell proliferation [ISS]
- nitric oxide biosynthetic process [ISS]
- omega-hydroxylase P450 pathway [TAS]
- oxidation-reduction process [TAS]
- positive regulation of JAK-STAT cascade [ISS]
- positive regulation of angiogenesis [ISS]
- positive regulation of apoptotic process [ISS]
- positive regulation vascular endothelial growth factor production [ISS]
- regulation of reactive oxygen species metabolic process [ISS]
- retinal blood vessel morphogenesis [ISS]
- retinal metabolic process [IDA]
- retinol metabolic process [IDA]
- small molecule metabolic process [TAS]
- steroid metabolic process [IDA]
- sterol metabolic process [TAS]
- trabecular meshwork development [ISS]
- visual perception [TAS]
- xenobiotic metabolic process [IDA, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Control of TurboID-dependent biotinylation intensity in proximity ligation screens.
Proximity biotinylation screens are a widely used strategy for the unbiased identification of interacting or vicinal proteins. The latest generation biotin ligase TurboID has broadened the range of potential applications, as this ligase promotes an intense and faster biotinylation, even in subcellular compartments like the endoplasmic reticulum. On the other hand, the uncontrollable high basal biotinylation rates deny the system's ... [more]
J Proteomics May. 15, 2023; 279();104886 [Pubmed: 36966971]
Throughput
- High Throughput
Additional Notes
- TurboID
Curated By
- BioGRID