BAIT
CNPY3
CAG4A, ERDA5, PRAT4A, TNRC5, HSPC084
canopy FGF signaling regulator 3
GO Process (2)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
ACSL4
ACS4, FACL4, LACS4, MRX63, MRX68
acyl-CoA synthetase long-chain family member 4
GO Process (9)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- cellular lipid metabolic process [TAS]
- lipid biosynthetic process [IDA]
- lipid metabolic process [IDA]
- long-chain fatty acid metabolic process [IDA]
- long-chain fatty-acyl-CoA biosynthetic process [TAS]
- negative regulation of prostaglandin secretion [IDA]
- positive regulation of cell growth [IDA]
- small molecule metabolic process [TAS]
- triglyceride biosynthetic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Control of TurboID-dependent biotinylation intensity in proximity ligation screens.
Proximity biotinylation screens are a widely used strategy for the unbiased identification of interacting or vicinal proteins. The latest generation biotin ligase TurboID has broadened the range of potential applications, as this ligase promotes an intense and faster biotinylation, even in subcellular compartments like the endoplasmic reticulum. On the other hand, the uncontrollable high basal biotinylation rates deny the system's ... [more]
J Proteomics May. 15, 2023; 279();104886 [Pubmed: 36966971]
Throughput
- High Throughput
Additional Notes
- TurboID
Curated By
- BioGRID