PAFAH1B1
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- acrosome assembly [ISS]
- actin cytoskeleton organization [ISS]
- adult locomotory behavior [IMP]
- brain morphogenesis [IMP]
- cerebral cortex development [IMP]
- corpus callosum morphogenesis [IMP]
- establishment of mitotic spindle orientation [IMP]
- hippocampus development [ISS]
- layer formation in cerebral cortex [ISS]
- learning or memory [ISS]
- microtubule cytoskeleton organization [ISS]
- microtubule organizing center organization [IMP]
- microtubule-based process [IDA]
- mitotic cell cycle [TAS]
- neuroblast proliferation [ISS]
- neuromuscular process controlling balance [IMP]
- neuron migration [IMP, ISS]
- platelet activating factor metabolic process [ISS]
- regulation of Rho GTPase activity [ISS]
- retrograde axon cargo transport [ISS]
- synaptic transmission [ISS]
- transmission of nerve impulse [ISS]
- vesicle transport along microtubule [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CCSER2
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Pulse-SILAC and interactomics reveal distinct DDB1-CUL4 associated factors (DCAFs), cellular functions, and protein substrates.
Cullin-RING finger ligases (CRLs) represent the largest family of ubiquitin ligases. They are responsible for the ubiquitination of ?20% of cellular proteins degraded through the proteasome, by catalyzing the transfer of E2-loaded ubiquitin to a substrate. Seven Cullins are described in vertebrates. Among them, CUL4 associates with DDB1 to form the CUL4-DDB1 ubiquitin ligase complex, which is involved in protein ... [more]
Throughput
- High Throughput
Additional Notes
- BioID
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
PAFAH1B1 CCSER2 | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 260 | BioGRID | 2998140 |
Curated By
- BioGRID