BAIT

PTEN

2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, MMAC1, TEP1
phosphatase and tensin homolog
GO Process (72)
GO Function (13)
GO Component (13)

Gene Ontology Biological Process

Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

Tibarewal P, Spinelli L, Maccario H, Leslie NR

PTEN is a phosphoinositide lipid phosphatase and an important tumour suppressor protein. PTEN function is reduced or lost in around a third of all human cancers through diverse mechanisms, from gene deletion to changes in the function of proteins which regulate PTEN through direct protein binding. Here we present data from SILAC (Stable Isotope Labelling by Amino acids in Cell ... [more]

Adv Biol Regul Oct. 04, 2023; ();100989 [Pubmed: 37839992]

Throughput

  • Low Throughput

Additional Notes

  • SILAC proteomics in U87MG cells

Curated By

  • BioGRID