BAIT
ANLN
FSGS8, Scraps, scra
anillin, actin binding protein
GO Process (3)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MTDH
3D3, AEG-1, AEG1, LYRIC, LYRIC/3D3
metadherin
GO Process (8)
GO Function (6)
GO Component (10)
Gene Ontology Biological Process
- lipopolysaccharide-mediated signaling pathway [IMP]
- negative regulation of apoptotic process [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- positive regulation of NF-kappaB transcription factor activity [IDA]
- positive regulation of angiogenesis [IDA]
- positive regulation of autophagy [IDA]
- positive regulation of protein kinase B signaling [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.
Anillin (ANLN) is a mitosis-related protein that promotes contractile ring formation and cytokinesis, but its cell cycle-dependent degradation mechanisms in cancer cells remain unclear. Here, we show that high expression of ANLN promotes cytokinesis and proliferation in esophageal squamous cell carcinoma (ESCC) cells and is associated with poor prognosis in ESCC patients. Furthermore, the findings of the study showed that ... [more]
Cell Death Differ Feb. 01, 2023; 30(2);527-543 [Pubmed: 36526897]
Throughput
- High Throughput
Curated By
- BioGRID