BAIT

BTG3

ANA, TOB5, TOB55, TOFA

BTG family, member 3

GO Process (2)

GO Function (1)

GO Component (1)

Gene Ontology Biological Process

negative regulation of cell proliferation [TAS]

negative regulation of mitotic cell cycle [IDA]

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

CRISPR Database HGNC Alliance of Genome Resources VEGA OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

HSP90AB1

D6S182, HSP84, HSP90B, HSPC2, HSPCB, RP1-302G2.1

heat shock protein 90kDa alpha (cytosolic), class B member 1

Alzheimer's Disease Project

GO Process (9)

GO Function (7)

GO Component (6)

Gene Ontology Biological Process

Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]

axon guidance [TAS]

innate immune response [TAS]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [TAS]

positive regulation of nitric oxide biosynthetic process [ISS]

regulation of interferon-gamma-mediated signaling pathway [IMP]

regulation of type I interferon-mediated signaling pathway [IMP]

response to unfolded protein [NAS]

Gene Ontology Molecular Function

MHC class II protein complex binding [IDA]
TPR domain binding [ISS]
double-stranded RNA binding [IDA]
kinase binding [IPI]
nitric-oxide synthase regulator activity [ISS]
poly(A) RNA binding [IDA]
protein binding [IPI]

Gene Ontology Cellular Component

COP9 signalosome [IDA]

cytoplasm [IDA]

extracellular vesicular exosome [IDA]

mitochondrion [IDA]

CRISPR Database OMIM HGNC Alliance of Genome Resources VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

Viard J, Loe-Mie Y, Daudin R, Khelfaoui M, Plancon C, Boland A, Tejedor F, Huganir RL, Kim E, Kinoshita M, Liu G, Haucke V, Moncion T, Yu E, Hindie V, Blehaut H, Mircher C, Herault Y, Deleuze JF, Rain JC, Simonneau M, Lepagnol-Bestel AM

Down syndrome (DS) is caused by human chromosome 21 (HSA21) trisomy. It is characterized by a poorly understood intellectual disability (ID). We studied two mouse models of DS, one with an extra copy of the <i>Dyrk1A</i> gene (189N3) and the other with an extra copy of the mouse Chr16 syntenic region (Dp(16)1Yey). RNA-seq analysis of the transcripts deregulated in the ... [more]

Life Sci Alliance Aug. 01, 2022; 5(12); [Pubmed: 35914814]

Throughput

High Throughput

Curated By

BioGRID