BAIT
RBM11
RNA binding motif protein 11
GO Process (2)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BHLHE40
BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14
basic helix-loop-helix family, member e40
GO Process (7)
GO Function (14)
GO Component (4)
Gene Ontology Biological Process
- circadian regulation of gene expression [IDA]
- entrainment of circadian clock by photoperiod [ISS]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- regulation of transcription, DNA-templated [NAS]
- transcription from RNA polymerase II promoter [IDA, ISS]
Gene Ontology Molecular Function- E-box binding [IDA]
- MRF binding [ISS]
- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISS]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [IDA]
- bHLH transcription factor binding [IPI]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription corepressor activity [IDA]
- E-box binding [IDA]
- MRF binding [ISS]
- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISS]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [IDA]
- bHLH transcription factor binding [IPI]
- protein binding [IPI]
- protein domain specific binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription corepressor activity [IDA]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.
Down syndrome (DS) is caused by human chromosome 21 (HSA21) trisomy. It is characterized by a poorly understood intellectual disability (ID). We studied two mouse models of DS, one with an extra copy of the <i>Dyrk1A</i> gene (189N3) and the other with an extra copy of the mouse Chr16 syntenic region (Dp(16)1Yey). RNA-seq analysis of the transcripts deregulated in the ... [more]
Life Sci Alliance Aug. 01, 2022; 5(12); [Pubmed: 35914814]
Throughput
- High Throughput
Curated By
- BioGRID