BAIT
RSPH1
CT79, RSP44, RSPH10A, TSA2, TSGA2
radial spoke head 1 homolog (Chlamydomonas)
GO Process (1)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Homo sapiens
PREY
CTGF
CCN2, HCS24, IGFBP8, NOV2
connective tissue growth factor
GO Process (13)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- cell adhesion [IBA]
- cell-cell signaling [IBA]
- cellular lipid metabolic process [TAS]
- epidermis development [TAS]
- gene expression [TAS]
- negative regulation of cell death [IBA]
- positive regulation of ERK1 and ERK2 cascade [IDA]
- positive regulation of JNK cascade [IDA]
- positive regulation of cell differentiation [IDA]
- positive regulation of stress fiber assembly [IDA]
- response to wounding [TAS]
- small molecule metabolic process [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.
Down syndrome (DS) is caused by human chromosome 21 (HSA21) trisomy. It is characterized by a poorly understood intellectual disability (ID). We studied two mouse models of DS, one with an extra copy of the <i>Dyrk1A</i> gene (189N3) and the other with an extra copy of the mouse Chr16 syntenic region (Dp(16)1Yey). RNA-seq analysis of the transcripts deregulated in the ... [more]
Life Sci Alliance Aug. 01, 2022; 5(12); [Pubmed: 35914814]
Throughput
- High Throughput
Curated By
- BioGRID