BAIT

PVRL3

CD113, CDW113, NECTIN-3, PPR3, PRR3, PVRR3
poliovirus receptor-related 3
Homo sapiens
PREY

MLLT4

AF6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
GO Process (4)
GO Function (2)
GO Component (6)
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

PICK-1: a scaffold protein that interacts with Nectins and JAMs at cell junctions.

Reymond N, Garrido-Urbani S, Borg JP, Dubreuil P, Lopez M

Nectin adhesion molecules are involved in the early steps of cell junction formation. Later during the polarisation process, Nectins are components of epithelial adherens junctions where they are indirectly associated with the E-cadherin/Catenins complex via the adaptator AF-6. To have a better understanding of Nectin-based cell junctions, we looked for some new Nectins' partners. We demonstrate that the scaffold molecule ... [more]

FEBS Lett Apr. 11, 2005; 579(10);2243-9 [Pubmed: 15811349]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
PVRL3 MLLT4
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-
MLLT4 PVRL3
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-
MLLT4 PVRL3
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-

Curated By

  • BioGRID